DNA Repair, Genetics, Biochemistry
A postdoctoral opportunity is available to explore the basis of chromosomal rearrangement in cancer by studying the molecular mechanisms of DNA double-strand break repair. The fellow will be able to choose from several related projects, including (1) novel genomic approaches to elucidate the nature of the assembly of the nonhomologous end joining core complex as well as 5’ resection, and (2) molecular and genetic characterization of the ligase, polymerase(s) and nuclease(s) required for nonhomologous end joining. All projects will start with yeast as a model organism and expand into mammalian systems as directed by the interests of the candidate.
The University of Michigan is consistently one of the top-ranked academic medical research institutions in the USA. Ann Arbor is a progressive and exciting community with many cultural opportunities, while maintaining the quietness of a smaller town.
Candidates should have a Ph.D. or M.D., and international peer-reviewed publications. A strong background in applied biochemistry and/or molecular biology is required, with a background in genetics preferred. Previous handling of yeast would be helpful, but is not required. Interested individuals should send a cover letter, CV, and the names of three references to Dr. Wilson.
Rotation student is always welcome!