Postdoctoral Fellowship
DNA
Repair, Genetics, Biochemistry
A
postdoctoral opportunity is available to explore the basis of chromosomal
rearrangement in cancer by studying the molecular mechanisms of DNA
double-strand break repair. The fellow will be able to choose from several
related projects, including (1) novel genomic approaches to elucidate the
nature of the assembly of the nonhomologous end joining core complex as well as
5’ resection, and (2) molecular and genetic characterization of the ligase,
polymerase(s) and nuclease(s) required for nonhomologous end joining. All projects will start with yeast as a model
organism and expand into mammalian systems as directed by the interests of the
candidate.
The
University of Michigan is consistently one of the top-ranked academic medical
research institutions in the USA. Ann Arbor is a progressive and exciting
community with many cultural opportunities, while maintaining the quietness of
a smaller town.
Candidates
should have a Ph.D. or M.D., and international peer-reviewed publications. A strong background in applied biochemistry and/or molecular
biology is required, with a background in genetics preferred. Previous handling
of yeast would be helpful, but is not required. Interested individuals should
send a cover letter, CV, and the names of three references to Dr. Wilson.
Rotation student is always welcome!