TEWLAB
publications (Updated 12/5/2012)
Chiruvella KK, Liang Z & Wilson TE. Repair of double
strand breaks by end-joining. DNA
Repair and Mutagenesis III Edition (Book Chapter), Cold Spring Harbor Perspectives in Biology
(In press)
(2012)
Arlt MF, Rajendran S, Birkeland SR, Wilson TE & Glover TW. De novo CNV formation in mouse embryonic stem cells occurs in the absence of Xrcc4-dependent nonhomologous end joining. PLoS Genet 8, e1002981 (2012). PubMed
Arlt MF, Wilson TE & Glover TW. Replication stress and mechanisms of CNV formation. Curr Opin Genet Dev 22, 204-210 (2012). PubMed
Arlt
MF, Ozdemir AC, Birkeland SR, Wilson TE & Glover
TW. Hydroxyurea induces de novo copy number variants in human cells.
Proc Natl Acad Sci U S A 108, 17360-17365 (2011). PubMed
Arlt MF, Ozdemir AC,
Birkeland SR, Lyons RH, Jr., Glover TW & Wilson TE.
Comparison of constitutional and replication
stress-induced genome structural variation by SNP array and mate-pair
sequencing. Genetics 187, 675-683 (2011). PubMed
McLaughlin HM, Sakaguchi
R, Liu C, Igarashi T, Pehlivan D, Chu K, Iyer R, Cruz P, Cherukuri PF, Hansen
NF, Mullikin JC, Program NCS, Biesecker LG, Wilson TE, Ionasescu V, Nicholson
G, Searby C, Talbot K, Vance JM, Zuchner S, Szigeti K, Lupski JR, Hou YM, Green
ED & Antonellis A. Compound heterozygosity for loss-of-function
lysyl-tRNA synthetase mutations in a patient with peripheral neuropathy. Am J Hum Genet 87, 560-566 (2010). PubMed
Lieber
MR & Wilson TE. SnapShot:
Nonhomologous DNA End Joining (NHEJ). Cell 142,
496-496.e491 (2010). PubMed
Brady GF, Galban
S, Liu X, Basrur V, Gitlin JD, Elenitoba-Johnson KS, Wilson TE & Duckett
CS. Regulation of the copper chaperone CCS by XIAP-mediated ubiquitination.
Mol Cell Biol 30, 1923-1936 (2010). PubMed
Birkeland SR, Jin N, Ozdemir AC, Lyons RH, Jr.,
Weisman LS & Wilson TE. Discovery
of mutations in Saccharomyces cerevisiae by pooled linkage analysis and
whole-genome sequencing. Genetics 186, 1127-1137
(2010).
PubMed
O'Konek JJ, Boucher PD, Iacco AA, Wilson TE, Shewach DS. MLH1 deficiency enhances tumor cell sensitivity
to ganciclovir.
Cancer Gene Ther 116:683-92
(2009). JOURNAL
Palmbos PL, Wu D, Daley JM, Wilson TE. Recruitment of Saccharomyces cerevisiae Dnl4-Lif1
complex to a double-strand break requires interactions with Yku80 and the Xrs2
FHA domain. Genetics 180:1809-19
(2008). JOURNAL
Wu D, Topper LM, Wilson TE. Recruitment
and dissociation of NHEJ proteins at a DNA double strand break in Saccharomyces
cerevisiae. Genetics 178:1237-1249
(2008). JOURNAL
Wilson TE. Nonhomologous
recombination. Wiley
Encyclopedia of Chemical Biology, online
publication
Chovanec M, Wilson TE. Restricting the ligation step of nonhomologous
end joining. DNA Repair
6:1890-1893 (2007). PubMed
Daley J, Wilson TE. Evidence
that base stacking potential in annealed 3' overhangs determines polymerase
utilization in yeast nonhomologous end joining. DNA Repair 7:67-76 (2007). JOURNAL
Wilson TE. Nonhomologous end joining:
mechanisms, conservation, and relationship to illegitimate recombination. Topics in Current Genetics 17: 487-512 (2007)
Link
Deshpande R, Wilson TE. Modes of interaction among yeast Nej1, Lif1 and Dnl4 proteins
and comparison to human XLF, XRCC4 and Lig4. DNA Repair 6:1507-1516 (2007). JOURNAL
Hentges P, Ahnes P, Pitcher RS, Bruce CK, Kysela B, Green A, Bianchi J, Wilson TE, Jackson SP,
Doherty AJ. Evolutionary
and functional conservation of the DNA nonhomologous
end-joining protein XLF/Cernunnos. J. Biol. Chem. 281:37517-37526 (2006). JOURNAL
Pitcher RS, Tonkin LM, Daley JM, Palmbos PL,
Green AJ, Velting TL, Brzostek
A, Korycka-Machala M, Cresawn
SC, Dziadek J, Hatfull GF,
Wilson TE, Doherty AJ. Mycobacteriophage exploit prokaryotic NHEJ to
facilitate genome circularization. Mol Cell. 23:743-8 (2006). JOURNAL
Pratt-Hyatt MJ, Kapadia1 KM, Wilson TE, Engelke DR. Increased
recombination between active tRNA genes. DNA and Cell Biology 25:
359-64 (2006). PubMed
Palmbos PL, Daley JM, Wilson TE. Mutations
of the Yku80 C-terminus and Xrs2 FHA domain specifically block yeast nonhomologous end-joining. Mol. Cell. Biol. 25:
10782-90 (2005). JOURNAL
Pitcher RS, Wilson TE, Doherty AJ. New
insights into NHEJ repair processes in prokaryotes. Cell Cycle 4: 675-78
(2005). PubMed
Daley JM, Palmbos PL, Wu
D, Wilson TE. Nonhomologous end
joining in yeast. Annual
Review of Genetics 39: 431-51 (2005) JOURNAL
Daley JM, Vander Laan RL,
Suresh A, Wilson TE. DNA joint dependence of
Pol X family polymerase action in nonhomologous end
joining. J
Biol. Chem. 280: 29030-7 (2005). JOURNAL
Karumbati AS, Wilson TE. Abrogation
of the Chk1-Pds1 checkpoint leads to tolerance of persistent single-strand breaks. Genetics 169: 1833-44 (2005). PubMed
Daley JM, Wilson TE. Rejoining
of DNA double-strand breaks as a function of overhang length. Mol. Cell. Biol. 25: 896-906 (2005). JOURNAL
Della M, Palmbos PL, Tseng
HM, Tonkin LM, Daley JM, Topper LM, Pitcher RS, Tomkinson
AE, Wilson TE, Doherty AJ. Mycobacterial Ku and Ligase
proteins constitute a two-component NHEJ repair machine. Science 306: 683-5 (2004). PubMed
Deshpande R, Wilson TE. Identification of DNA 3’ phosphatase active site residues and
their differential role in DNA binding, Mg2+ coordination and catalysis. Biochemistry 43: 8579-89
(2004). PubMed
Karumbati AS, Deshpande
RA, Jilani A, Vance JR, Ramotar
D, Wilson TE. The role of yeast DNA 3'
phosphatase Tpp1 and Rad1/Rad10 endonuclease in processing spontaneous and
induced base lesions. J. Biol. Chem. 278: 31434-43 (2003). PubMed
Yu K, Chedin F, Hsieh CL,
Wilson TE, Lieber MR. R-loops
at immunoglobulin class switch regions in the chromosomes of stimulated B
cells. Nat. Immunol.
4: 442-51(2003). PubMed
Wilson TE, Palmbos PL,
Topper LM. Nonhomologous end-joining: bacteria join
the chromosome break dance. TIBS 28:
62-66 (2003). PubMed
Wilson TE. A
genomics-based screen for yeast mutants with an altered
recombination/end-joining repair ratio. Genetics 162: 677-88
(2002). PubMed
Vance JR, Wilson TE. Yeast
Tdp1 and Rad1-Rad10 function as redundant pathways for repairing Top1
replicative damage. Proc. Natl. Acad. Sci. USA 99: 13669-74 (2002). PubMed
Karathanasis E, Wilson TE. Enhancement of Saccharomyces cerevisiae end-joining efficiency
by stationary phase transition but not by impairment of recombination. Genetics 161: 1015-27 (2002). PubMed
Vance JR, Wilson TE. Repair of
DNA strand breaks by the overlapping functions of lesion-specific and
non-lesion-specific DNA 3’ phosphatases. Mol. Cell. Biol. 21: 7191-7198 (2001). PubMed
Vance JR, Wilson TE. Uncoupling of 3’ phosphatase and 5’ kinase functions in budding
yeast: Characterization of S. cerevisiae
DNA 3’ phosphatase (TPP1). J. Biol. Chem. 276: 15073-81 (2001). PubMed
Wilson TE, Lieber MR. Efficient processing
of DNA ends during yeast nonhomologous end-joining:
evidence for a DNA polymerase beta (POL4)-dependent pathway. J. Biol. Chem. 274:
23599-609 (1999). PubMed